Both the Palisade and Pilot have child safety locks to prevent children from opening the rear doors. The Palisade has power child safety locks, allowing the driver to activate and deactivate them from the driver's seat and to know when they're engaged. The Pilot’s child locks have to be individually engaged at each rear door with a manual switch. The driver can’t know the status of the locks without opening the doors and checking them.
Both the Palisade and Pilot have rear cross-traffic warning, but the Palisade has Rear Cross-Traffic Collision-Avoidance Assist (automatically applies the brakes) to better prevent a collision when backing near traffic. The Pilot’s Cross Traffic Monitor doesn’t automatically brake.
Both the Palisade and the Pilot have standard driver and passenger frontal airbags, front side-impact airbags, driver knee airbags, side-impact head airbags, front seatbelt pretensioners, front wheel drive, height adjustable front shoulder belts, four-wheel antilock brakes, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, daytime running lights, lane departure warning systems, blind spot warning systems, rearview cameras, rear cross-path warning, driver alert monitors, available all wheel drive and around view monitors.

